Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 67.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 325.00 | |
50 mg | In stock | $ 566.00 | |
100 mg | In stock | $ 790.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 117.00 |
Description | Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED) |
In vivo | Investigated right ventricular hypertrophy (RVH) and IL-1 levels in lung fragments. The number of cases of RVH was significantly higher in the monocrotaline group than in the lodenafil and control groups, as were mPAP and IL-1 levels. Lodenafil can prevent monocrotaline-induced PH, RVH, and inflammation[1]. |
Animal Research | Thirty male Sprague-Dawley rats were randomly divided into three groups: control; monocrotaline (experimental model); and lodenafil (experimental model followed by lodenafil treatment, 5 mg/kg daily for 28 days) Mean pulmonary artery pressure (mPAP) was obtained by right heart catheterization[1]. |
Synonyms | Hydroxyhomosildenafil |
Molecular Weight | 504.6 |
Formula | C23H32N6O5S |
CAS No. | 139755-85-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (495.44 mM)
You can also refer to dose conversion for different animals. More
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Lodenafil 139755-85-4 Metabolism PDE inhibit Hydroxyhomosildenafil Phosphodiesterase (PDE) Inhibitor inhibitor