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ML406

Catalog No. T8694Cas No. 774589-47-8

ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM)

ML406

ML406

Purity: 98.69%
Catalog No. T8694Cas No. 774589-47-8
ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM)
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$48In Stock
10 mg$81In Stock
25 mg$163In Stock
50 mg$247In Stock
100 mg$372In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:98.69%
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Product Introduction

Bioactivity
Description
ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM)
Targets&IC50
BioA:IC50 : 30 nM
Chemical Properties
Molecular Weight352.38
FormulaC20H20N2O4
Cas No.774589-47-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (283.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8378 mL14.1892 mL28.3785 mL141.8923 mL
5 mM0.5676 mL2.8378 mL5.6757 mL28.3785 mL
10 mM0.2838 mL1.4189 mL2.8378 mL14.1892 mL
20 mM0.1419 mL0.7095 mL1.4189 mL7.0946 mL
50 mM0.0568 mL0.2838 mL0.5676 mL2.8378 mL
100 mM0.0284 mL0.1419 mL0.2838 mL1.4189 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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