anti-tubercular

Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.

ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM)

Antitubercular agent-33, a 2-aminothiazole derivative, exhibits potent anti-tubercular activity against Mycobacterium tuberculosis (Mtb) [1].

Porson exhibited anti-tubercular activity against Mycobacterium tuberculosis H37Rv in vitro and MICs values of 40.0 μg/mL.

Antitubercular agent-24 (Compound 1) exhibits anti-tubercular properties against M. tuberculosis H37Rv, demonstrating an extracellular IC50 of 0.83 μM and an intracellular IC50 of 0.17 μM [1].

ACH-702 is an agent of anti-tubercular. ACH-702 is an effective, bactericidal compound with activity against many antibiotic-resistant pathogens.

Antitubercular agent-25 (Compound 28) is an anti-tubercular agent with an extracellular IC50 of 0.42 μM and an intracellular IC50 of 0.20 μM against M. tuberculosis H37Rv, and it demonstrates good metabolic stability.

Sudoterb has anti-tubercular activity.

MmpL3-IN-3 (Compound 12), an MmpL3 inhibitor, exhibits potent anti-tuberculosis activity with a minimum inhibitory concentration (MIC) of 0.1 μM against H37Rv and demonstrates good metabolic stability in mouse liver microsomes. This compound is valuable for anti-tubercular research [1].