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Midecamycin

Catalog No. T5037 CAS 35457-80-8

Synonyms: Turimycin P3, Medecamycin A1, Espinomycin A, Platenomycin B1, Rubimycin, Antibiotic SF-837

Midecamycin, an acetoxy-substituted macrolide Antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.

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Midecamycin, CAS 35457-80-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Midecamycin, an acetoxy-substituted macrolide antibiotic, has effective on gram-positive and gram-negative bacteria acts by inhibiting bacterial protein synthesis.
In vitro	Midecamycin inhibits the majority of streptococci, staphylococci, and strains of Haemophilus and Listeria at concentrations of less than 3.1 μg/mL [1]. Midecamycin is a novel 16-membered macrolide antibiotic, which is produced by Streptomyces mycarofaciens [2].

Synonyms	Turimycin P3, Medecamycin A1, Espinomycin A, Platenomycin B1, Rubimycin, Antibiotic SF-837
Molecular Weight	813.97
Formula	C41H67NO15
CAS No.	35457-80-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 50 mg/mL

Ethanol: 50 mg/mL

H2O: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Neu HC. In vitro activity of midecamycin, a new macrolide antibiotic. Antimicrob Agents Chemother. 1983 Sep;24(3):443-4. 2. Cong L, et al. Cloning and characterization of genes encoded in dTDP-D-mycaminose biosynthetic pathway from amidecamycin-producing strain, Streptomyces mycarofaciens. Acta Biochim Biophys Sin (Shanghai). 2007 Mar;39(3):187-93.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Midecamycin 35457-80-8 Microbiology/Virology Antibacterial Antibiotic SF837 Antibiotic SF 837 Bacterial inhibit Antibiotic SF837 Turimycin P3 Medecamycin A1 Inhibitor SF-837 Espinomycin A Platenomycin B1 SF 837 Rubimycin Antibiotic SF-837 inhibitor

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