Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 143.00 | |
25 mg | In stock | $ 287.00 | |
50 mg | In stock | $ 497.00 | |
100 mg | In stock | $ 723.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease. |
In vivo | Consumption of a standard high-fat breakfast within 30 minutes before administration of Miglustat hydrochloride significantly reduced peak exposure but did not significantly affect the extent of systemic exposure to Miglustat hydrochloride. The Cmax decreased by 36% on average following administration with food. AUC showed a modest (14%) decrease with food, but the 90% confidence interval was within the acceptance limit of 80% to 125%. Tmax was prolonged from 2.5 (1.0-4.0) hours in the fasted state to 4.5 (1.5-8.0) hours in the fed state, whereas the apparent terminal half-life was approximately 8 hours and not affected by food[1]. |
Synonyms | NB-DNJ hydrochloride, N-Butyldeoxynojirimycin hydrochloride, OGT918 hydrochloride |
Molecular Weight | 255.74 |
Formula | C10H22ClNO4 |
CAS No. | 210110-90-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 34 mg/mL (132.95 mM)
DMSO: 60 mg/mL (234.61 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Miglustat hydrochloride 210110-90-0 Metabolism Transferase N-Butyldeoxynojirimycin Hydrochloride N-Butyldeoxynojirimycin NB-DNJ hydrochloride OGT-918 type I gaucher disease Miglustat oral Glucosylceramide Synthase (GCS) OGT918 Miglustat Hydrochloride OGT918 Hydrochloride ceramide glucosyltransferase NB-DNJ Inhibitor inhibit OGT 918 OGT 918 Hydrochloride N-Butyldeoxynojirimycin hydrochloride OGT-918 Hydrochloride OGT918 hydrochloride NB-DNJ Hydrochloride inhibitor