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NE-100 hydrochloride
🥰Excellent
Catalog No. T20797Cas No. 149409-57-4
Alias NE-100 Hydrochloride, NE100 Hydrochloride, NE-100 HCl, NE 100 Hydrochloride, NE 100 HCl
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-induced hippocampal cell death.
NE-100 hydrochloride
🥰Excellent
Purity: 98.85%
Catalog No. T20797Alias NE-100 Hydrochloride, NE100 Hydrochloride, NE-100 HCl, NE 100 Hydrochloride, NE 100 HClCas No. 149409-57-4
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-induced hippocampal cell death.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $38 | In Stock | |
| 2 mg | $52 | In Stock | |
| 5 mg | $84 | In Stock | |
| 10 mg | $139 | In Stock | |
| 25 mg | $233 | In Stock | |
| 50 mg | $347 | In Stock | |
| 100 mg | $516 | In Stock | |
| 200 mg | $736 | In Stock | |
| 500 mg | $1,090 | In Stock |
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Purity:98.85%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-induced hippocampal cell death. |
| Targets&IC50 | σ1:4.16 nM |
| Alias | NE-100 Hydrochloride, NE100 Hydrochloride, NE-100 HCl, NE 100 Hydrochloride, NE 100 HCl |
| Molecular Weight | 391.98 |
| Formula | C23H34ClNO2 |
| Cas No. | 149409-57-4 |
| Smiles | Cl.CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: Soluble H2O: 15 mg/mL, Sonication and heating to 60℃ are recommended. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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