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NKL 22

NKL 22
NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
Catalog No. T3206Cas No. 537034-15-4
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Purity:96.16%
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NKL 22

Purity: 96.16%
Catalog No. T3206Alias PAOA, Histone Deacetylase Inhibitor IVCas No. 537034-15-4

NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$29In Stock
25 mg$58In Stock
50 mg$94In Stock
100 mg$148In Stock
200 mg$219In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Product Introduction

Bioactivity
Description
NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
Targets&IC50
HDAC8:5 μM (IC50), HDAC1:0.199 μM (IC50), HDAC3:0.069 μM (IC50), HDAC2:1.59 μM (IC50)
AliasPAOA, Histone Deacetylase Inhibitor IV
Chemical Properties
Molecular Weight325.4
FormulaC19H23N3O2
Cas No.537034-15-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (153.66 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0731 mL15.3657 mL30.7314 mL153.6570 mL
5 mM0.6146 mL3.0731 mL6.1463 mL30.7314 mL
10 mM0.3073 mL1.5366 mL3.0731 mL15.3657 mL
20 mM0.1537 mL0.7683 mL1.5366 mL7.6829 mL
50 mM0.0615 mL0.3073 mL0.6146 mL3.0731 mL
100 mM0.0307 mL0.1537 mL0.3073 mL1.5366 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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