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NKL 22

Catalog No. T3206Cas No. 537034-15-4
Alias PAOA, Histone Deacetylase Inhibitor IV

NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.

NKL 22

NKL 22

Purity: 96.16%
Catalog No. T3206Alias PAOA, Histone Deacetylase Inhibitor IVCas No. 537034-15-4
NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
Pack SizePriceAvailabilityQuantity
10 mg$29In Stock
25 mg$58In Stock
50 mg$94In Stock
100 mg$148In Stock
200 mg$219In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:96.16%
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Product Introduction

Bioactivity
Description
NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.
Targets&IC50
HDAC8:5 μM (IC50), HDAC1:0.199 μM (IC50), HDAC3:0.069 μM (IC50), HDAC2:1.59 μM (IC50)
AliasPAOA, Histone Deacetylase Inhibitor IV
Chemical Properties
Molecular Weight325.4
FormulaC19H23N3O2
Cas No.537034-15-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (153.66 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0731 mL15.3657 mL30.7314 mL153.6570 mL
5 mM0.6146 mL3.0731 mL6.1463 mL30.7314 mL
10 mM0.3073 mL1.5366 mL3.0731 mL15.3657 mL
20 mM0.1537 mL0.7683 mL1.5366 mL7.6829 mL
50 mM0.0615 mL0.3073 mL0.6146 mL3.0731 mL
100 mM0.0307 mL0.1537 mL0.3073 mL1.5366 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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