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NP118809

NP118809
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
Catalog No. T7334Cas No. 41332-24-5
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Purity:98.68%
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NP118809

Catalog No. T7334Cas No. 41332-24-5
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 mg$81In Stock
200 mg$98In Stock
500 mg$126In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
Targets&IC50
Ca2+ channel, N-type:0.11 μM
In vitro
NP118809 with a total linker length of 3 carbons (n = 1) and which exhibited approximately a 500-fold increased N-type channel blockade compared to compounds in this series with linkers either shorter (n = 0, 2a) or longer (n = 2 4, (2c e). Examination of the effect of NP118809 on functional L-type calcium channel activity showed that this compound was approximately 111-fold more selective for N-type channels[1]
Alias39-1B4
Chemical Properties
Molecular Weight460.61
FormulaC32H32N2O
Cas No.41332-24-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.61 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1710 mL10.8552 mL21.7103 mL108.5517 mL
5 mM0.4342 mL2.1710 mL4.3421 mL21.7103 mL
10 mM0.2171 mL1.0855 mL2.1710 mL10.8552 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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