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Omaciclovir
😃Good
Catalog No. T28234Cas No. 124265-89-0
Alias H2G, H 2G, ABT-091, ABT091, ABT 091, (-)-2HM-HBG
Omaciclovir (ABT-091) is a selective herpesvirus herpesvirus replication inhibitor and a nucleoside analog with antiviral activity for the study of herpesvirus infections.
Omaciclovir
😃Good
Purity: 99.46%
Catalog No. T28234Alias H2G, H 2G, ABT-091, ABT091, ABT 091, (-)-2HM-HBGCas No. 124265-89-0
Omaciclovir (ABT-091) is a selective herpesvirus herpesvirus replication inhibitor and a nucleoside analog with antiviral activity for the study of herpesvirus infections.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $132 | In Stock | |
| 25 mg | $1,270 | 10-14 weeks | |
| 50 mg | $1,650 | 10-14 weeks | |
| 100 mg | $2,610 | 10-14 weeks |
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Purity:99.46%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Omaciclovir (ABT-091) is a selective herpesvirus herpesvirus replication inhibitor and a nucleoside analog with antiviral activity for the study of herpesvirus infections. |
| Targets&IC50 | MeWo Emily:0.047 μM (EC50), MeWo Molly:0.048 μM (EC50), MRC-5 Molly:0.62 μM (EC50), MeWo VZV-32:0.015 μM (EC50), MeWo VZ30:0.016 μM (EC50), MRC-5 VZV-32:0.72 μM (EC50), MeWo VZ11:0.035 μM (EC50) |
| In vitro | Omaciclovir is a nucleoside analog with inhibitory activity in vitro against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), Epstein-Barr virus, and human herpesvirus 6. Additionally, Omaciclovir demonstrates significant antiviral activity against various human herpesviruses, with half-maximal effective concentrations (EC50) of EC50=0.72 μM, EC50=0.62 μM, EC50=0.015 μM, EC50=0.048 μM, EC50=0.047 μM, EC50=0.035 μM, and EC50=0.016 μM in MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively. [1] |
| In vivo | Omaciclovir has also shown efficacy in monkeys infected with simian varicella virus. [1] |
| Alias | H2G, H 2G, ABT-091, ABT091, ABT 091, (-)-2HM-HBG |
| Molecular Weight | 253.26 |
| Formula | C10H15N5O3 |
| Cas No. | 124265-89-0 |
| Smiles | C([C@@H](CCO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2 |
| Relative Density. | 1.68g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 200 mg/mL (789.7 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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