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PD 117519

Catalog No. T7509Cas No. 96392-15-3
Alias CI947

PD 117519 (CI947) is an agonist of the adenosine receptor.

PD 117519

PD 117519

Purity: 99.98%
Catalog No. T7509Alias CI947Cas No. 96392-15-3
PD 117519 (CI947) is an agonist of the adenosine receptor.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$50In Stock
25 mg$89In Stock
50 mg$163In Stock
100 mg$238In Stock
200 mg$353In Stock
1 mL x 10 mM (in DMSO)$33In Stock
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Purity:99.98%
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Product Introduction

Bioactivity
Description
PD 117519 (CI947) is an agonist of the adenosine receptor.
In vivo
PD 117519?selectively binds to adenosine A2 receptors (IC50 = 30 μM) over A1 receptors (IC50 = 810 μM) in rat brain membranes.?PD 117519 increases heart rate and decreases systolic blood pressure in normotensive dogs when administered at doses of 2 or 10 mg/kg[1].
AliasCI947
Chemical Properties
Molecular Weight383.4
FormulaC19H21N5O4
Cas No.96392-15-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (260.82 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6082 mL13.0412 mL26.0824 mL130.4121 mL
5 mM0.5216 mL2.6082 mL5.2165 mL26.0824 mL
10 mM0.2608 mL1.3041 mL2.6082 mL13.0412 mL
20 mM0.1304 mL0.6521 mL1.3041 mL6.5206 mL
50 mM0.0522 mL0.2608 mL0.5216 mL2.6082 mL
100 mM0.0261 mL0.1304 mL0.2608 mL1.3041 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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