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PD 174265

Catalog No. T28339Cas No. 216163-53-0
Alias PD-174265, PD174265, N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.

PD 174265

PD 174265

Purity: 98.88%
Catalog No. T28339Alias PD-174265, PD174265, N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamideCas No. 216163-53-0
PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$38In Stock
25 mg$57In Stock
50 mg$80In Stock
100 mg$116In Stock
1 mL x 10 mM (in DMSO)$38In Stock
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Purity:98.88%
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Product Introduction

Bioactivity
Description
PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
AliasPD-174265, PD174265, N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide
Chemical Properties
Molecular Weight371.23
FormulaC17H15BrN4O
Cas No.216163-53-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mg/mL (26.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6937 mL13.4687 mL26.9375 mL134.6874 mL
5 mM0.5387 mL2.6937 mL5.3875 mL26.9375 mL
10 mM0.2694 mL1.3469 mL2.6937 mL13.4687 mL
20 mM0.1347 mL0.6734 mL1.3469 mL6.7344 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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