Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
2 mg | In stock | $ 45.00 | |
5 mg | In stock | $ 71.00 | |
10 mg | In stock | $ 105.00 | |
25 mg | In stock | $ 220.00 | |
50 mg | In stock | $ 335.00 | |
100 mg | In stock | $ 498.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 71.00 |
Description | PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer. |
Targets&IC50 | SMARCA4:55 nM(Kd), SMARCA2A:110 nM(Kd), SMARCA2B:72 nM(Kd) |
In vitro | PFI-3 shows a significant selectivity for PB1(5) and SMARCA2/4 over 36 other tested kinases. [1] |
Synonyms | PFI 3 |
Molecular Weight | 321.37 |
Formula | C19H19N3O2 |
CAS No. | 1819363-80-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 32.1 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PFI-3 1819363-80-8 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor PFI 3 PFI3 inhibit inhibitor