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PFI-3

Catalog No. T6939   CAS 1819363-80-8
Synonyms: PFI 3

PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.

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PFI-3 Chemical Structure
PFI-3, CAS 1819363-80-8
Pack Size Availability Price/USD Quantity
1 mg In stock $ 32.00
2 mg In stock $ 45.00
5 mg In stock $ 71.00
10 mg In stock $ 105.00
25 mg In stock $ 220.00
50 mg In stock $ 335.00
100 mg In stock $ 498.00
1 mL * 10 mM (in DMSO) In stock $ 71.00
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Purity: 99.94%
Purity: 99.71%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
Targets&IC50 SMARCA4:55 nM(Kd), SMARCA2A:110 nM(Kd), SMARCA2B:72 nM(Kd)
In vitro PFI-3 shows a significant selectivity for PB1(5) and SMARCA2/4 over 36 other tested kinases. [1]
Synonyms PFI 3
Molecular Weight 321.37
Formula C19H19N3O2
CAS No. 1819363-80-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 32.1 mg/mL(100 mM)

TargetMolReferences and Literature

1. Structural Genomics Consortium (SGC).

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Histone Modification Compound Library Inhibitor Library Reprogramming Compound Library NO PAINS Compound Library Immuno-Oncology Compound Library Anti-COVID-19 Compound Library Bioactive Compounds Library Max Epigenetics Compound Library Chromatin Modification Compound Library

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Keywords

PFI-3 1819363-80-8 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor PFI 3 PFI3 inhibit inhibitor

 

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