Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 74.00 | |
10 mg | In stock | $ 129.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 525.00 | |
100 mg | In stock | $ 748.00 | |
500 mg | In stock | $ 1,520.00 |
Description | 1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints. |
Targets&IC50 | MGL:93 nM |
Source |
Synonyms | Celastrol methyl ester |
Molecular Weight | 464.64 |
Formula | C30H40O4 |
CAS No. | 1258-84-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.64 mg/mL (9.99 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Pristimerin 1258-84-0 Microbiology/Virology NF-Κb NF-κB Antibacterial Bacterial Celastrol methyl ester Inhibitor inhibit inhibitor