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Pyrithioxin dihydrochloride
🥰Excellent
Catalog No. T20735Cas No. 10049-83-9
Alias Vitamin B6 disulfide dihydrochloride, Pyritinol dihydrochloride, Pyrithioxine hydrochloride, Pyrithioxine HCl
Pyrithioxin dihydrochloride (Pyrithioxine HCl) has anti-nociceptive and anti-allodynic effects, can promote the metabolism of glucose and amino acids in the brain, improve systemic assimilation, and can be used to study neurological diseases such as atherosclerosis. Pyrithioxin dihydrochloride can induce severe cholestatic hepatitis.
Pyrithioxin dihydrochloride
🥰Excellent
Purity: 98%
Catalog No. T20735Alias Vitamin B6 disulfide dihydrochloride, Pyritinol dihydrochloride, Pyrithioxine hydrochloride, Pyrithioxine HClCas No. 10049-83-9
Pyrithioxin dihydrochloride (Pyrithioxine HCl) has anti-nociceptive and anti-allodynic effects, can promote the metabolism of glucose and amino acids in the brain, improve systemic assimilation, and can be used to study neurological diseases such as atherosclerosis. Pyrithioxin dihydrochloride can induce severe cholestatic hepatitis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | 30 € | In Stock | |
| 100 mg | 45 € | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Pyrithioxin dihydrochloride (Pyrithioxine HCl) has anti-nociceptive and anti-allodynic effects, can promote the metabolism of glucose and amino acids in the brain, improve systemic assimilation, and can be used to study neurological diseases such as atherosclerosis. Pyrithioxin dihydrochloride can induce severe cholestatic hepatitis. |
| In vivo | METHODS: The effect of Pyrithioxin dihydrochloride on children with learning disabilities was tested under strict double-blind conditions in 67 students in a class with learning disabilities aged 11 to 16 years who received either Pyrithioxin dihydrochloride (300 mg, 24 hours) or placebo for 6 months. Effects on cognitive function. RESULTS:Pyrithioxin dihydrochloride had different effects on different subjects. None of the 22 parameters showed a statistically significant treatment effect in terms of mean performance. Variability was significantly higher in the Pyrithioxin dihydrochloride group (F = 1.85-2.33, P less than 0.05 and less than 0.02, respectively). [1] |
| Alias | Vitamin B6 disulfide dihydrochloride, Pyritinol dihydrochloride, Pyrithioxine hydrochloride, Pyrithioxine HCl |
| Molecular Weight | 441.39 |
| Formula | C16H22Cl2N2O4S2 |
| Cas No. | 10049-83-9 |
| Smiles | OC1=C(CO)C(CSSCC2=CN=C(C)C(O)=C2CO)=CN=C1C.Cl.Cl |
| Relative Density. | 1.448g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL（113.28 mM), Sonication is recommended. H2O: 40 mg/mL（90.62 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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