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R(+)-IAA-94

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Catalog No. T12788Cas No. 54197-31-8
Alias R(+)-Methylindazone

R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).

R(+)-IAA-94

R(+)-IAA-94

🥰Excellent
Purity: 99.22%
Catalog No. T12788Alias R(+)-MethylindazoneCas No. 54197-31-8
R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
Pack SizePriceAvailabilityQuantity
2 mg29 €In Stock
5 mg52 €In Stock
10 mg84 €In Stock
25 mg160 €In Stock
50 mg282 €In Stock
100 mg417 €In Stock
1 mL x 10 mM (in DMSO)92 €In Stock
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Purity:99.22%
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Product Introduction

Bioactivity
Description
R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
In vitro
IAA-94 has been utilized for its high affinity to modulate chloride channel activity, serving as a tool to investigate the channels' dynamics and functions. This property has also facilitated the isolation and reconstitution of these proteins [1][2].
AliasR(+)-Methylindazone
Chemical Properties
Molecular Weight357.23
FormulaC17H18Cl2O4
Cas No.54197-31-8
SmilesC[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C1CCCC1
Relative Density.1.401 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90 mg/mL (251.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7993 mL13.9966 mL27.9932 mL139.9658 mL
5 mM0.5599 mL2.7993 mL5.5986 mL27.9932 mL
10 mM0.2799 mL1.3997 mL2.7993 mL13.9966 mL
20 mM0.1400 mL0.6998 mL1.3997 mL6.9983 mL
50 mM0.0560 mL0.2799 mL0.5599 mL2.7993 mL
100 mM0.0280 mL0.1400 mL0.2799 mL1.3997 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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