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Raf inhibitor 2
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
Catalog No. T4194Cas No. 220904-99-4
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Purity:98.53%
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Raf inhibitor 2
Catalog No. T4194Alias CID-25014542, CID25014542, CID 25014542Cas No. 220904-99-4
Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $34 | In Stock | |
| 5 mg | $56 | In Stock | |
| 10 mg | $88 | In Stock | |
| 25 mg | $167 | In Stock | |
| 50 mg | $253 | In Stock | |
| 100 mg | $368 | In Stock | |
| 200 mg | $517 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
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Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.
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CitedRegorafenib Cited
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Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity.
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Sorafenib tosylate Cited
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Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases. |
| Alias | CID-25014542, CID25014542, CID 25014542 |
| Molecular Weight | 429.49 |
| Formula | C15H8Br2ClNO2 |
| Cas No. | 220904-99-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (69.85 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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