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Rafabegron

🥰Excellent
Catalog No. T34256Cas No. 244081-42-3
Alias TAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677

Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.

Rafabegron

Rafabegron

🥰Excellent
Purity: 100%
Catalog No. T34256Alias TAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677Cas No. 244081-42-3
Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.
Pack SizePriceAvailabilityQuantity
1 mg$290In Stock
5 mg$713In Stock
10 mg$987In Stock
25 mg$1,480In Stock
50 mg$1,980In Stock
100 mg$2,730In Stock
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Purity:100%
ee:100%
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Product Introduction

Bioactivity
Description
Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.
AliasTAK-677, TAK677, TAK 677, AD-9677, AD9677, AD 9677
Chemical Properties
Molecular Weight402.87
FormulaC21H23ClN2O4
Cas No.244081-42-3
SmilesO(CC(O)=O)C1=C2C(C(C[C@H](NC[C@H](O)C3=CC(Cl)=CC=C3)C)=CN2)=CC=C1
Relative Density.1.345g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (111.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4822 mL12.4110 mL24.8219 mL124.1095 mL
5 mM0.4964 mL2.4822 mL4.9644 mL24.8219 mL
10 mM0.2482 mL1.2411 mL2.4822 mL12.4110 mL
20 mM0.1241 mL0.6205 mL1.2411 mL6.2055 mL
50 mM0.0496 mL0.2482 mL0.4964 mL2.4822 mL
100 mM0.0248 mL0.1241 mL0.2482 mL1.2411 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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