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Refametinib R enantiomer

Catalog No. T12697Cas No. 923032-38-6
Alias Refametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomer

Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.

Refametinib R enantiomer

Refametinib R enantiomer

Purity: 99.43%
Catalog No. T12697Alias Refametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomerCas No. 923032-38-6
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
Pack SizePriceAvailabilityQuantity
1 mg$85In Stock
5 mg$210In Stock
10 mg$310In Stock
25 mg$586In Stock
50 mg$780In Stock
100 mg$1,090In Stock
500 mg$2,180In Stock
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Purity:99.43%
ee:98.92%
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Product Introduction

Bioactivity
Description
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
Targets&IC50
MEK:2-15 nM (EC50)
In vitro
Refametinib R enantiomer is the R enantiomer of Refametinib. It functions as an MEK inhibitor and is used in the treatment of cancer and other hyperproliferative diseases.[1]
AliasRefametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomer
Chemical Properties
Molecular Weight572.34
FormulaC19H20F3IN2O5S
Cas No.923032-38-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (96.1 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7472 mL8.7361 mL17.4721 mL87.3607 mL
5 mM0.3494 mL1.7472 mL3.4944 mL17.4721 mL
10 mM0.1747 mL0.8736 mL1.7472 mL8.7361 mL
20 mM0.0874 mL0.4368 mL0.8736 mL4.3680 mL
50 mM0.0349 mL0.1747 mL0.3494 mL1.7472 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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