Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine receptor, which induces coronary vasodilation. This leads to an increase in coronary blood flow and enhances myocardial perfusion. Compared to adenosine, regadenoson has a longer half-life and shows higher selectivity towards the A2A adenosine receptor. This agent is a very weak agonist for the A1 adenosine receptor and has negligible affinity for the A2B and A3 adenosine receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 59.00 | |
10 mg | In stock | $ 93.00 | |
25 mg | In stock | $ 183.00 | |
50 mg | In stock | $ 287.00 | |
100 mg | In stock | $ 438.00 | |
500 mg | In stock | $ 985.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 66.00 |
Description | Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine receptor, which induces coronary vasodilation. This leads to an increase in coronary blood flow and enhances myocardial perfusion. Compared to adenosine, regadenoson has a longer half-life and shows higher selectivity towards the A2A adenosine receptor. This agent is a very weak agonist for the A1 adenosine receptor and has negligible affinity for the A2B and A3 adenosine receptors. |
Targets&IC50 | A2AR:290 nM(Ki) |
Synonyms | CVT-3146, Lexiscan |
Molecular Weight | 390.35 |
Formula | C15H18N8O5 |
CAS No. | 313348-27-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9 mg/mL (23.06 mM)
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Regadenoson 313348-27-5 GPCR/G Protein Neuroscience Adenosine Receptor coronary myocardial perfusion imaging CVT3146 inhibit CBF CVT-3146 P1 receptor CVT 3146 Inhibitor BBB Lexiscan inhibitor