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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $108 | In Stock | |
5 mg | $239 | In Stock | |
10 mg | $383 | In Stock | |
25 mg | $653 | In Stock | |
50 mg | $893 | In Stock | |
100 mg | $1,220 | In Stock | |
1 mL x 10 mM (in DMSO) | $263 | In Stock |
Description | SIRT-IN-2 is a potent SIRT1/2/3 inhibitor [IC50s of 4, 1, and 7 μM, respectively]. |
In vitro | SIRT-IN-2 is one of the most potent truncated pan SIRT1/ 2/3 inhibitor(IC50 values are 4, 4, 7 μM, respectively). SIRT-IN-2 binds identically in the catalytic active site (RMS=0.29 ), occupying the nicotinamide C-pocket and acetyl lysine substrate channel. |
Molecular Weight | 383.49 |
Formula | C15H21N5O3S2 |
Cas No. | 1431411-66-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 62.5 mg/mL (151.24 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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