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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $95 | In Stock | |
2 mg | $139 | In Stock | |
5 mg | $235 | In Stock | |
10 mg | $357 | In Stock | |
25 mg | $590 | In Stock | |
50 mg | $852 | In Stock | |
100 mg | $1,180 | In Stock | |
500 mg | $2,350 | In Stock |
Description | SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis. |
In vitro | SJB3-019A with IC50 of 0.0781 μM is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity. |
Molecular Weight | 276.25 |
Formula | C16H8N2O3 |
Cas No. | 2070015-29-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: 1 mg/ml, Sonication is recommended. ![]() |
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