Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 95.00 | |
2 mg | In stock | $ 139.00 | |
5 mg | In stock | $ 235.00 | |
10 mg | In stock | $ 357.00 | |
25 mg | In stock | $ 590.00 | |
50 mg | In stock | $ 852.00 | |
100 mg | In stock | $ 1,180.00 | |
500 mg | In stock | $ 2,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 218.00 |
Description | SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis. |
Targets&IC50 | ID1:78.1 nM , ID1:78.1 nM |
In vitro | SJB3-019A with IC50 of 0.0781 μM is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity. |
Molecular Weight | 276.25 |
Formula | C16H8N2O3 |
CAS No. | 2070015-29-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.0 mg/mL (32.6 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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SJB3-019A 2070015-29-9 Cell Cycle/Checkpoint DNA Damage/DNA Repair Others Ubiquitination DUB SJB-3-019A SJB3 019A SJB3019A inhibitor inhibit