Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 123.00 | |
5 mg | In stock | $ 263.00 | |
10 mg | In stock | $ 396.00 | |
25 mg | In stock | $ 665.00 | |
50 mg | In stock | $ 947.00 | |
100 mg | In stock | $ 1,280.00 | |
500 mg | In stock | $ 2,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 332.00 |
Description | SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity. |
Targets&IC50 | LNCaPAR+ cells:0.2 μM |
In vitro | SK33 has a significantly potent activity (IC50:0.2 μM) in LNCaPAR+ cells. SK33 decreases cells enter S-phase in LNCaP cells. In LNCaP/BicR cells, increasing concentrations of SK33 for 96 hours results in a dose-dependent response and an inhibition of cell growth(IC50 : 5 μM for SK33). |
In vivo | AR transcriptional activity inhibited by SK33 after 50 mg/kg treatment for 24 hours. |
Molecular Weight | 500.31 |
Formula | C20H13F9N2O3 |
CAS No. | 1928724-23-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (109.93 mM)
You can also refer to dose conversion for different animals. More
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