Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
500 mg | In stock | $ 2,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 311.00 |
Description | Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies. |
Targets&IC50 | σ1 receptor:1.06 nM(Ki) |
In vitro | Sigma‑1 receptor antagonist 1 exhibits a high binding affinity to σ1R receptor with Ki of 1.06 nM and good σ-1/2 selectivity (1344-fold)[1]. |
In vivo | In mice formalin model and rats CCI models of neuropathic pain, Sigma‑1 receptor antagonist 1 exerts dose-dependent antinociceptive effects[1]. |
Molecular Weight | 380.31 |
Formula | C19H23Cl2N3O |
CAS No. | 1639220-19-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6 mg/mL (15.78 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Sigma-1 receptor antagonist 1 1639220-19-1 GPCR/G Protein Sigma receptor inhibit σ-1 receptor antagonist 1 Inhibitor Sigma Receptor Sigma 1 receptor antagonist 1 Sigma1 receptor antagonist 1 inhibitor