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TBAJ-587

TBAJ-587
TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. BAJ-587 has more potent activity against M. tuberculosis and better efficacy in animal models of TB.
Catalog No. T5997Cas No. 2252316-16-6
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Purity:99.12%
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TBAJ-587

Purity: 99.12%
Catalog No. T5997Cas No. 2252316-16-6

TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 μg/mL in MABA and LORA assay, respectively. BAJ-587 has more potent activity against M. tuberculosis and better efficacy in animal models of TB.
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Pack SizePriceAvailabilityQuantity
1 mg$116In Stock
5 mg$289In Stock
10 mg$452In Stock
25 mg$745In Stock
50 mg$1,050In Stock
100 mg$1,390In Stock
1 mL x 10 mM (in DMSO)$389In Stock
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Product Introduction

Bioactivity
Description
TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. BAJ-587 has more potent activity against M. tuberculosis and better efficacy in animal mode
Chemical Properties
Molecular Weight614.5
FormulaC30H33BrFN3O5
Cas No.2252316-16-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (48.82 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6273 mL8.1367 mL16.2734 mL81.3670 mL
5 mM0.3255 mL1.6273 mL3.2547 mL16.2734 mL
10 mM0.1627 mL0.8137 mL1.6273 mL8.1367 mL
20 mM0.0814 mL0.4068 mL0.8137 mL4.0683 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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