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Tin-protoporphyrin IX dichloride
Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses.
Catalog No. T13161Cas No. 14325-05-4
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Purity:98%
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Tin-protoporphyrin IX dichloride
Catalog No. T13161Cas No. 14325-05-4
Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $45 | In Stock | |
| 5 mg | $106 | In Stock | |
| 10 mg | $172 | In Stock | |
| 25 mg | $288 | In Stock | |
| 50 mg | $432 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses. |
| Targets&IC50 | HO-1: |
| In vitro | In Capan-1, CD18/HPAF, and PDAC cells, Tin protoporphyrin IX dichloride (20 μM, 50 μM; 24 or 72 hours) inhibited proliferation of Capan-1 and CD18/HPAF cells and inhibited growth of PDAC cells at 50 μM[1]. |
| In vivo | In male and female athymic nude mice with PDAC cell-derived xenograft tumors, Tin protoporphyrin IX dichloride (5 mg/kg; Intraperitoneal injection; on days 1, 4, 6, 8, 11, 13, 15, 18, and 20) inhibited tumor growth and sensitized tumors to chemotherapy (Gemcitabine)[1]. |
| Alias | SnPPIX, SnPPIX dichloride |
| Molecular Weight | 750.26 |
| Formula | C34H32Cl2N4O4Sn |
| Cas No. | 14325-05-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | 0.1M NaOH: 10 mg/mL (13.3 mM), Sonication is recommended.  DMSO: 5 mg/mL (6.6 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO/0.1M NaOH
0.1M NaOH
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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