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Home > Microbiology&virology > HCV Protease > Velpatasvir

Velpatasvir

Catalog No. T3334    CAS 1377049-84-7    Synonyms: GS-5816

Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Pack Size Availability Price/USD Quantity
10 mg In stock 50.00
25 mg In stock 78.00
50 mg In stock 117.00
100 mg In stock 193.00
200 mg In stock 347.00
1 mL * 10 mM (in DMSO) In stock 65.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Receptor:

HCV NS5A;

Chemical Information:
Molecular Weight 883.02
Formula C49H54N8O8
CAS Number 1377049-84-7
Solubility

DMSO: 91 mg/mL (103.1 mM), Need ultrasonic and warming

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.