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Home > Microbiology&virology > HCV Protease > Velpatasvir

Velpatasvir

Catalog No. T3334    CAS 1377049-84-7    Synonyms: GS-5816

Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Pack Size Availability Price/USD Quantity
10 mg In stock 50.00
25 mg In stock 78.00
50 mg In stock 117.00
100 mg In stock 193.00
200 mg In stock 347.00
1 mL * 10 mM (in DMSO) In stock 65.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Velpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Receptor:

HCV NS5A;

Chemical Information:
Molecular Weight 883.02
Formula C49H54N8O8
CAS Number 1377049-84-7
Solubility

DMSO: 91 mg/mL (103.1 mM), Need ultrasonic and warming

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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