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Chromatin/Epigenetic Epigenetic Reader Domain XD14

XD14

Catalog No. T19935   CAS 1370888-71-3
Purity 98.40% Datasheet

XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).

XD14, CAS 1370888-71-3
Pack Size Availability Price/USD Quantity
1 mg In stock 159.00
5 mg In stock 325.00
10 mg In stock 520.00
25 mg In stock 1017.00
50 mg In stock 1525.00
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Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
Targets&IC50 BRD4(1) :ic50 160 nM (Kd),   BRD2(1) :ic50 170 nM (Kd),   BRD3(1) :ic50 380 nM (Kd),   BRD3(2) :ic50 490 nM (Kd),   BRD2(2) :ic50 830 nM (Kd),   BRD4(2) :ic50 850 nM (Kd),  
Synonyms
Purity 98.40%
Appearance solid
Molecular Weight 421.51
Formula C20H27N3O5S
CAS No. 1370888-71-3

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Daqiang P , Michel K , Lucas W , et al. Metabolic Response to XD14 Treatment in Human Breast Cancer Cell Line MCF-7[J]. International Journal of Molecular ences, 2016, 17(10).

Related Products

Related compounds with same targets
Diflunisal Curcumin MS436 Molibresib GSK 5959 PFI-4 J147 BET bromodomain inhibitor

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