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YM348

Catalog No. T17275 CAS 372163-84-3

YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).

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YM348, CAS 372163-84-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).
Targets&IC50	5-HT2C Receptor:0.89 nM （ki）, 5-HT2C Receptor:1 nM （EC50）, 5-HT2A Receptor:13 nM （ki）, 5-HT2A Receptor:93 nM （EC50）, 5-HT2B Receptor:2.5 nM （ki）, 5-HT2B Receptor:3.2 nM （EC50）

Molecular Weight	243.3
Formula	C14H17N3O
CAS No.	372163-84-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

YM348 372163-84-3 G蛋白偶联受体神经科学 5-HT Receptor YM-348 Inhibitor inhibitor inhibit

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