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Acetyl-L-carnitine
Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of neurological disorders like Alzheimer's disease.
Catalog No. T26551Cas No. 3040-38-8
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Acetyl-L-carnitine
Catalog No. T26551Cas No. 3040-38-8
Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of neurological disorders like Alzheimer's disease.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $258 | In Stock | |
| 5 mg | $642 | In Stock | |
| 10 mg | $913 | In Stock | |
| 25 mg | $1,370 | In Stock | |
| 50 mg | $1,850 | In Stock | |
| 100 mg | $2,500 | In Stock | |
| 500 mg | $4,900 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of neurological disorders like Alzheimer's disease. |
| In vivo | Three different paradigms were used to deliver Acetyl L-carnitine (ALCAR) to aging Fischer 344/NHsd rats. Rats in each condition had their hearing evaluated by auditory brainstem responses before, during, and after treatment. First, 24-month-old rats were given ALCAR (100 mg/kg dissolved 25 mg/ml in saline) by IP injection daily for one month. Second, 18-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Third, 15-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Control rats in each condition received saline by i.p. injection or gavage. The current study does not provide evidence that age-related hearing loss in the Fischer 344/NHsd rat can be altered with systemic administration of ALCAR.[2] |
| Alias | RO 447190, L-Acetylcarnitine, LAC, L-O-Acetylcarnitine, ALCAR, Acetyl L carnitine |
| Molecular Weight | 203.24 |
| Formula | C9H17NO4 |
| Cas No. | 3040-38-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 2.03 mg/mL (10 mM), Sonication is recommended.  H2O: 2.03 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO/H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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