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Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of neurological disorders like Alzheimer's disease.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $258 | In Stock | |
5 mg | $642 | In Stock | |
10 mg | $913 | In Stock | |
25 mg | $1,370 | In Stock | |
50 mg | $1,850 | In Stock | |
100 mg | $2,500 | In Stock | |
500 mg | $4,900 | In Stock |
Description | Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of neurological disorders like Alzheimer's disease. |
In vivo | Three different paradigms were used to deliver Acetyl L-carnitine (ALCAR) to aging Fischer 344/NHsd rats. Rats in each condition had their hearing evaluated by auditory brainstem responses before, during, and after treatment. First, 24-month-old rats were given ALCAR (100 mg/kg dissolved 25 mg/ml in saline) by IP injection daily for one month. Second, 18-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Third, 15-month-old rats were given ALCAR (100 mg/kg) by oral gavage for 90 days. Control rats in each condition received saline by i.p. injection or gavage. The current study does not provide evidence that age-related hearing loss in the Fischer 344/NHsd rat can be altered with systemic administration of ALCAR.[2] |
Alias | RO 447190, L-O-Acetylcarnitine, L-Acetylcarnitine, LAC, ALCAR, Acetyl L carnitine |
Molecular Weight | 203.24 |
Formula | C9H17NO4 |
Cas No. | 3040-38-8 |
Smiles | CC(=O)OC(CC([O-])=O)C[N+](C)(C)C |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 2.03 mg/mL (10 mM), Sonication is recommended. H2O: 2.03 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO/H2O
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