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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | AHR antagonist 7 (compound 4j), a selective aryl hydrocarbon receptor (AhR) antagonist with high affinity, demonstrates a dissociation constant (K i) of 1.4 nM [1]. |
In vitro | In HepG2 cells, the AHR antagonist 7 (CAY10464; 100 nM) reduces CYP1A1 mRNA expression and counteracts the Benzo[a]pyrene-induced suppression of apolipoprotein A-I (apo A-I) gene expression [2]. |
Molecular Weight | 279.16 |
Formula | C15H12Cl2O |
Cas No. | 688348-37-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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