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Alliin

Alliin
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Purity:99.62%
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Alliin

Catalog No. T5764Cas No. 556-27-4
Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS-induced NF-κB activation and inflammatory response. Alliin might be used as an anti-inflammatory agent in the treatment of ALI.
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Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$96In Stock
10 mg$165In Stock
25 mg$319In Stock
50 mg$479In Stock
100 mg$686In Stock
1 mL x 10 mM (in DMSO)$83In Stock
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Product Introduction

Bioactivity
Description
Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS-induced NF-κB activation and inflammatory response. Alliin might be used as an anti-inflammatory agent in the treatment of ALI.
In vivo
LPS-induced ALI was induced in BALB/c mice by intranasal instillation of LPS.?Alliin was administered intraperitoneally to mice 1 h after LPS treatment.?Alliin markedly inhibited lung myeloperoxidase (MPO) activity and wet/dry (W/D) ratio induced by LPS.?Alliin also inhibited TNF-α and IL-1β in the bronchoalveolar lavage fluid (BALF) induced by LPS.?Furthermore, LPS-induced lung pathological injury was attenuated by treatment of alliin.?LPS-induced NF-κB activation was significantly inhibited by alliin.?In addition, the expression of peroxisome proliferator-activated receptor γ (PPARγ) was up-regulated by treatment of alliin.?Taken together,Alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS-induced NF-κB activation and inflammatory response.
Alias(S)-3-(Allylsulphinyl)-L-alanine
Chemical Properties
Molecular Weight177.22
FormulaC6H11NO3S
Cas No.556-27-4
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 3 mg/mL (16.92 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.6427 mL28.2135 mL56.4270 mL282.1352 mL
5 mM1.1285 mL5.6427 mL11.2854 mL56.4270 mL
10 mM0.5643 mL2.8214 mL5.6427 mL28.2135 mL

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