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AN2718

AN2718
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Purity:100%
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AN2718

Catalog No. T4040Cas No. 174672-06-1
AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$43In Stock
10 mg$61In Stock
25 mg$97In Stock
50 mg$158In Stock
100 mg$239In Stock
500 mg$597In Stock
1 mL x 10 mM (in DMSO)$47In Stock
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Product Introduction

Bioactivity
Description
AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness.
In vitro
AN2718 inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM for A. fumigatus and C. albicans LeuRS, respectively)
Chemical Properties
Molecular Weight168.39
FormulaC7H6BClO2
Cas No.174672-06-1
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (356.34 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.9386 mL29.6930 mL59.3859 mL296.9297 mL
5 mM1.1877 mL5.9386 mL11.8772 mL59.3859 mL
10 mM0.5939 mL2.9693 mL5.9386 mL29.6930 mL
20 mM0.2969 mL1.4846 mL2.9693 mL14.8465 mL
50 mM0.1188 mL0.5939 mL1.1877 mL5.9386 mL
100 mM0.0594 mL0.2969 mL0.5939 mL2.9693 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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