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AP1189 acetate
🥰Excellent
Catalog No. T9596Cas No. 959850-74-9
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
AP1189 acetate
🥰Excellent
Purity: 98.73%
Catalog No. T9596Cas No. 959850-74-9
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $41 | In Stock | |
| 5 mg | $83 | In Stock | |
| 10 mg | $136 | In Stock | |
| 25 mg | $247 | In Stock | |
| 50 mg | $368 | In Stock | |
| 100 mg | $523 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $109 | In Stock |
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Purity:98.73%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors. |
| In vitro | Added to macrophage cultures, AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes[1]. |
| In vivo | Oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ～3-fold[1]. |
| Molecular Weight | 358.35 |
| Formula | C16H18N6O4 |
| Cas No. | 959850-74-9 |
| Smiles | O=[N+](C1=CC=CC=C1N2C(/C=C/C=N/NC(N)=N)=CC=C2)[O-].CC(O)=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (139.53 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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