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Artelinic acid

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TargetMol
Catalog No. T10378Cas No. 120020-26-0

Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.

Artelinic acid

Artelinic acid

🥰Excellent
TargetMol
Purity: 97.80%
Catalog No. T10378Cas No. 120020-26-0
Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.
Pack SizePriceAvailabilityQuantity
1 mg$100In Stock
5 mg$247In Stock
10 mg$396In Stock
25 mg$745In Stock
50 mg$1,160In Stock
100 mg$1,650In Stock
200 mg$2,230In Stock
1 mL x 10 mM (in DMSO)$318In Stock
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Purity:97.80%
ee:96.92%
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Product Introduction

Bioactivity
Description
Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.
In vivo
In adult male beagle dogs aged 3-5 years, artelinic acid (10 mg/kg; i.v.) had an elimination half-life of 0.37 hours, a clearance of 14.99 mL/min/kg, a volume of distribution at steady state of 9.52 L, and an AUC0-12h of 11219 ng h/mL[1].
Chemical Properties
Molecular Weight418.48
FormulaC23H30O7
Cas No.120020-26-0
Smiles[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OCc1ccc(cc1)C(O)=O)[C@@H]2C)O4
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (191.17 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3896 mL11.9480 mL23.8960 mL119.4800 mL
5 mM0.4779 mL2.3896 mL4.7792 mL23.8960 mL
10 mM0.2390 mL1.1948 mL2.3896 mL11.9480 mL
20 mM0.1195 mL0.5974 mL1.1948 mL5.9740 mL
50 mM0.0478 mL0.2390 mL0.4779 mL2.3896 mL
100 mM0.0239 mL0.1195 mL0.2390 mL1.1948 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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