Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 513.00 | |
10 mg | In stock | $ 747.00 | |
25 mg | In stock | $ 1,160.00 | |
50 mg | In stock | $ 1,560.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 763.00 |
Description | ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM. |
Targets&IC50 | KRas (G12C):40 nM (IC50) |
Molecular Weight | 747.85 |
Formula | C40H48F3N7O4 |
CAS No. | 2241719-73-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (334.29 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ASP2453 2241719-73-1 GPCR/G Protein MAPK Ras inhibit ASP-2453 Inhibitor ASP 2453 inhibitor