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Auristatin F

Auristatin F
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Purity:99.25%
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Auristatin F

Catalog No. T14349Cas No. 163768-50-1
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$58In Stock
10 mg$79In Stock
25 mg$122In Stock
50 mg$173In Stock
100 mg$253In Stock
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Product Introduction

Bioactivity
Description
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
In vitro
Auristatin F and Monomethyl Auristatin F (MMAF) are highly potent cytotoxic agents utilized in ADCs[1].
Chemical Properties
Molecular Weight745.99
FormulaC40H67N5O8
Cas No.163768-50-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 195 mg/mL (261.40 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.3405 mL6.7025 mL13.4050 mL67.0250 mL
5 mM0.2681 mL1.3405 mL2.6810 mL13.4050 mL
10 mM0.1341 mL0.6703 mL1.3405 mL6.7025 mL
20 mM0.0670 mL0.3351 mL0.6703 mL3.3513 mL
50 mM0.0268 mL0.1341 mL0.2681 mL1.3405 mL
100 mM0.0134 mL0.0670 mL0.1341 mL0.6703 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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