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Auristatin F

Name: Auristatin F
Brand: TargetMol
SKU: T14349
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T14349Cas No. 163768-50-1

Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.

Auristatin F

🥰Excellent

Purity: 99.25%

Catalog No. T14349Cas No. 163768-50-1

Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.

Pack Size	Price	Availability
5 mg	$35	In Stock
10 mg	$47	In Stock
25 mg	$73	In Stock
50 mg	$103	In Stock
100 mg	$153	In Stock

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Purity:99.25%

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COA LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
In vitro	Auristatin F and Monomethyl Auristatin F (MMAF) are highly potent cytotoxic agents utilized in ADCs[1].

Chemical Properties

Molecular Weight	745.99
Formula	C₄₀H₆₇N₅O₈
Cas No.	163768-50-1
Smiles	[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@H](C(C)C)N(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Relative Density.	1.112 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 195 mg/mL (261.40 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.3405 mL	6.7025 mL	13.4050 mL	67.0250 mL
5 mM	0.2681 mL	1.3405 mL	2.6810 mL	13.4050 mL
10 mM	0.1341 mL	0.6703 mL	1.3405 mL	6.7025 mL
20 mM	0.0670 mL	0.3351 mL	0.6703 mL	3.3513 mL
50 mM	0.0268 mL	0.1341 mL	0.2681 mL	1.3405 mL
100 mM	0.0134 mL	0.0670 mL	0.1341 mL	0.6703 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc