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Search Results for " vascular "

Targets

420

Compounds

82

Natural Products

493

Recombinant Proteins

6

Libraries

Cat No. Product Name Synonyms Targets
T12598 Pz-1 VEGFR , c-RET
Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.
T9724 VEGFR2-IN-2 Others
VEGFR2-IN-2 has anti-inflammatory and analgesic activities.
TQ0321 BIBF 1202 VEGFR
BIBF 1202 is a VEGFR2 kinase inhibitor (IC50: 62 nM).
T9979 VEGFR-2-IN-29 VEGFR
VEGFR-2-IN-29 is a VEGFR2 inhibitor.
T2446 KI8751 EGFR , VEGFR , FGFR , PDGFR , c-Kit
KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.
T14349 Auristatin F Microtubule Associated
Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.
T8844 Diflapolin Others , FLAP , Epoxide Hydrolase
Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T6012 SAR131675 SAR 131675 VEGFR
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T11520 GW806742X MLK , VEGFR
GW806742X is an inhibitor of Mixed Lineage Kinase Domain-Like protein (MLKL) which binds the MLKL pseudokinase domain (Kd: 9.3 μM) with anti-necroptosis activity. GW806742X has activity against VEGFR2.
T2419 BMS-794833 VEGFR , c-Met/HGFR
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.
TQ0041 Ningetinib Tosylate VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T3638 Leukadherin-1 Integrin , Complement System
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.
T8157 Centhaquin PMZ-2010,Centhaquine Others
Centhaquin (Centhaquine)e is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock
T2642 PD173074 Apoptosis , EGFR , VEGFR , FGFR , IGF-1R , Src
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.
T21445 Naphazoline AK-Con,Naphcon-a,Clear Eyes,All Clear Adrenergic Receptor
Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.
T5475 ZD-4190 EGFR , VEGFR
ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pathways, utilized in cancer treatment.
T0446 Naphazoline hydrochloride Albalon,Rhinantin,Naphazoline HCl Adrenergic Receptor
Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.
T4288 HVEGF-IN-1 VEGFR
hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.
T16975 TAK-593 VEGFR , PDGFR
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).
T2064 Semaxinib SU5416 VEGFR
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the...
T3566 SU5205 SU 5205 VEGFR
SU5205 is a VEGFR2 inhibitor.
T1656 Vandetanib ZD6474 Apoptosis , EGFR , VEGFR , Autophagy
Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
T9928 Ranibizumab VEGFR
Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121, and VEGF165. Ranibizumab's ability to selectively target and n...
T2656 Fruquintinib HMPL-013 VEGFR
Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
T0993 Methoxamine hydrochloride Methoxamine HCl Adrenergic Receptor
Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
T21593 AAL-993 VEGFR
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogeni...
T21712 BAY 41-8543 Others , Guanylate cyclase
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
T6036 Brivanib BMS-540215 EGFR , VEGFR , FGFR , Autophagy
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
T3691 (Rac)-SAR131675 SAR131675 VEGFR
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...
T3599 BFH772 BFH-722 VEGFR
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation ...
T7945 SU14813 VEGFR , PDGFR , c-Kit
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
T1754 ZM 306416 CB 676475 VEGFR , Bcr-Abl , Src
ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
T6996 SU 5402 SU5402 VEGFR , FGFR , PDGFR
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.
T4026 SU5408 VEGFR2 Kinase Inhibitor I VEGFR
SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.
T6517 Golvatinib E-7050 VEGFR , c-Met/HGFR
Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ...
T9473 4SC-203 FLT
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...
T5466 Tyrosine kinase-IN-1 VEGFR , FGFR , FLT , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively)
T3569 SU5214 SU 5214 VEGFR , Tyrosinase
SU5214 is a modulator of tyrosine kinase signal transduction.
T1498 Indapamide Veroxil,Noranat,Tertensif Potassium Channel
Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
T5458 Darusentan Lu-135252 Endothelin Receptor
Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries
T15185 Lucitanib E-3810 VEGFR , FGFR
Lucitanib (E-3810) is a novel VEGFR and FGFR inhibitor. It potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 (IC50s: 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively).
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T7123 AMG-47a VEGFR , p38 MAPK , JAK , Src
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...
T1449 Hydrochlorothiazide HCTZ Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T22459 Xanthinol Nicotinate Angioamin,Complamin Others
Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.
T2415 PP121 Apoptosis , VEGFR , Bcr-Abl , PDGFR , Src , mTOR , Hck
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).
T7611 ODM-203 VEGFR , FGFR
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.

Compounds

Pz-1
T12598
Synonym:
Target: VEGFR, c-RET
VEGFR2-IN-2
T9724
Synonym:
Target: Others
BIBF 1202
TQ0321
Synonym:
Target: VEGFR
VEGFR-2-IN-29
T9979
Synonym:
Target: VEGFR
KI8751
T2446
Synonym:
Target: EGFR, VEGFR, FGFR, PDGFR, c-Kit
Auristatin F
T14349
Synonym:
Target: Microtubule Associated
Diflapolin
T8844
Synonym:
Target: Others, FLAP, Epoxide Hydrolase
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
SAR131675
T6012
Synonym: SAR 131675
Target: VEGFR
Ramucirumab
T9929
Synonym:
Target: VEGFR
GW806742X
T11520
Synonym:
Target: MLK, VEGFR
BMS-794833
T2419
Synonym:
Target: VEGFR, c-Met/HGFR
Ningetinib Tosylate
TQ0041
Synonym:
Target: VEGFR, c-Met/HGFR, TAM Receptor
Leukadherin-1
T3638
Synonym:
Target: Integrin, Complement System
Centhaquin
T8157
Synonym: PMZ-2010,Centhaquine
Target: Others
PD173074
T2642
Synonym:
Target: Apoptosis, EGFR, VEGFR, FGFR, IGF-1R, Src
Naphazoline
T21445
Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear
Target: Adrenergic Receptor
ZD-4190
T5475
Synonym:
Target: EGFR, VEGFR
Naphazoline hydrochloride
T0446
Synonym: Albalon,Rhinantin,Naphazoline HCl
Target: Adrenergic Receptor
hVEGF-IN-1
T4288
Synonym:
Target: VEGFR
TAK-593
T16975
Synonym:
Target: VEGFR, PDGFR
Semaxinib
T2064
Synonym: SU5416
Target: VEGFR
SU5205
T3566
Synonym: SU 5205
Target: VEGFR
Vandetanib
T1656
Synonym: ZD6474
Target: Apoptosis, EGFR, VEGFR, Autophagy
Ranibizumab
T9928
Synonym:
Target: VEGFR
Fruquintinib
T2656
Synonym: HMPL-013
Target: VEGFR
Methoxamine hydrochloride
T0993
Synonym: Methoxamine HCl
Target: Adrenergic Receptor
AAL-993
T21593
Synonym:
Target: VEGFR
BAY 41-8543
T21712
Synonym:
Target: Others, Guanylate cyclase
Brivanib
T6036
Synonym: BMS-540215
Target: EGFR, VEGFR, FGFR, Autophagy
(Rac)-SAR131675
T3691
Synonym: SAR131675
Target: VEGFR
BFH772
T3599
Synonym: BFH-722
Target: VEGFR
SU14813
T7945
Synonym:
Target: VEGFR, PDGFR, c-Kit
ZM 306416
T1754
Synonym: CB 676475
Target: VEGFR, Bcr-Abl, Src
SU 5402
T6996
Synonym: SU5402
Target: VEGFR, FGFR, PDGFR
SU5408
T4026
Synonym: VEGFR2 Kinase Inhibitor I
Target: VEGFR
Golvatinib
T6517
Synonym: E-7050
Target: VEGFR, c-Met/HGFR
4SC-203
T9473
Synonym:
Target: FLT
Tyrosine kinase-IN-1
T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
SU5214
T3569
Synonym: SU 5214
Target: VEGFR, Tyrosinase
Indapamide
T1498
Synonym: Veroxil,Noranat,Tertensif
Target: Potassium Channel
Darusentan
T5458
Synonym: Lu-135252
Target: Endothelin Receptor
Lucitanib
T15185
Synonym: E-3810
Target: VEGFR, FGFR
JK-P3
T4425
Synonym:
Target: VEGFR
AMG-47a
T7123
Synonym:
Target: VEGFR, p38 MAPK, JAK, Src
Hydrochlorothiazide
T1449
Synonym: HCTZ
Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad
Xanthinol Nicotinate
T22459
Synonym: Angioamin,Complamin
Target: Others
PP121
T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
ODM-203
T7611
Synonym:
Target: VEGFR, FGFR
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
1 2 3 4 5 6 7 8 9
Cat No. Product Name Synonyms Targets
T8198 Visnagin Others
Visnagin has acute hypotensive, anti-inflammatory, and neuroprotective effects, it protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase.
T8213 Isolinderalactone NOS , STAT
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
T8206 Cycleanine Others
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.
T17280 (Z)-Guggulsterone Apoptosis , VEGFR , Akt
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
T4A2456 Gamabufotalin Gamabufagin COX
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.
T3S1591 Notoginsenoside Fc Others , Autophagy
1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.
T1431 Khellin Amicardine,Methafrone,Visammin EGFR , Others
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
T0853 Adenosine D-Adenosine,Adenine riboside Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
T2906 Tanshinone IIA Tanshinone B,Dan Shen ketone VEGFR
Tanshinone IIA (Tanshinone B)(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T3S0364 L-Arginine L-Arg,(S)-(+)-Arginine IL Receptor , Endogenous Metabolite , NO Synthase
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...
T19180 Adrenic Acid cis-7,10,13,16-Docosatetraenoic acid Endogenous Metabolite
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a member of the class of compounds known as very-long-chain fatty acids. Adrenic Acid can be found in blood and in human myelin tissue.
T3673 Mollugin Rubimaillin HER , JAK
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
TN2019 Orobol 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon BCL , Caspase , PI3K
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...
T1152 Albendazole SKF-62979 HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T0070 Pentoxifylline Oxpentifylline,PTX,BL-191 HIV Protease , PDE , Adenosine Receptor , Autophagy
Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...
T1205 Chloramphenicol Chlornitromycin,Levomycetin,Chloromycetin ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
T13108 Pamufetinib H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115 VEGFR , c-Met/HGFR
Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase(IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively).
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...
TWA2417 Sodium taurocholate Taurocholate Sodium Others
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...
T6S1373 Casticin Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin STAT
1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate...
T0878 Diosmin Venosmine,Diosmil,Barosmin Aryl Hydrocarbon Receptor , Norepinephrine
Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.
T8178 Acetagastrodin Acegastrodine Others
Acetagastrodin (Acegastrodine) has an antispasmodic effect on vascular smooth muscle.
T19711 Desmosterol Desmesterol,24-Dehydrocholesterol Endogenous Metabolite
Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.
T3S1816 Parishin B Others
1. Parishin B can prevent vascular dementia.
T5S0833 Astragaloside III Antioxidant
Astragaloside III has cardioprotective effects as well as causing improvement in cognitive function. It can be used in the prevention of cardio-cerebral vascular diseases. It also is antioxidant.
TN1683 Gentisin DNA/RNA Synthesis
Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.
T6S0721 Orientin Lutexin,Luteolin-8-glucoside Others
1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...
T6S0655 Corynoxeine ERK
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
T6S1367 Procyanidin B2 Proanthocyanidin B2 Reactive Oxygen Species , NOD
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ...
T4S0999 (2S)-Isoxanthohumol Isoxanthohumol Virus Protease , HSV
1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic ...
TN1996 Nothofagin ERK , IL Receptor , TNF
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usef...
T0530 Flavanone 2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one Others , Aromatase
Flavanone (2-Phenylchroman-4-one)s from citrus fruits have also been shown to exert beneficial effects on human vascular function. In particular, chronic interventions with orange juice, or the pure flavanone hesperidin,...
TN1087 Deoxypodophyllotoxin Apoptosis , Microtubule Associated , Autophagy
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.
T5684 Ethyl 3,4-dihydroxybenzoate Apoptosis , Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , NO Synthase , Autophagy
Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.
T7044 Norepinephrine Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol MMP , Endogenous Metabolite , Adrenergic Receptor , Autophagy
Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloprotei...
T3123 Allicin ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
T3427 Polydatin Piceid,Polydotin Peceid Apoptosis , Mitophagy , NF-κB , Autophagy
Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In th...
T4S1102 Liensinine diperchlorate Liensinine-Perchlorate Mitophagy , Others , Autophagy
Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus. It inhibits late autophagy by blocking autophagosome-lysosome fusion and exhibits biological activities such as...
TN1042 Chebulic acid Others
Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity,which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits t...
T2520 Desloratadine Sch34117,NSC 675447 Endogenous Metabolite , Histamine Receptor
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot...
T3794 Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose Influenza Virus
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...
T3403 Glabridin Q-100692,KB-289522,LS-176045 Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T5S1889 Yunaconitine Guayewuanine B Others
1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po...
T6429 Caffeic Acid Phenethyl Ester Phenylethyl Caffeate,CAPE Apoptosis , NF-κB
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...
T6S1784 Brazilin Natural Red 24,Braziletto,Brasilin,Superbresiline Apoptosis , Others , AMPK , Autophagy
1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific sign...
TN1969 N-(p-Coumaroyl) serotonin PDGFR
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower. N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving...
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
T6S1572 Sauchinone ERK , p38 MAPK , NF-κB
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...
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Natural Products

Visnagin
T8198
Synonym:
Target: Others
Isolinderalactone
T8213
Synonym:
Target: NOS, STAT
Cycleanine
T8206
Synonym:
Target: Others
(Z)-Guggulsterone
T17280
Synonym:
Target: Apoptosis, VEGFR, Akt
Gamabufotalin
T4A2456
Synonym: Gamabufagin
Target: COX
Notoginsenoside Fc
T3S1591
Synonym:
Target: Others, Autophagy
Khellin
T1431
Synonym: Amicardine,Methafrone,Visammin
Target: EGFR, Others
Adenosine
T0853
Synonym: D-Adenosine,Adenine riboside
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy
Tanshinone IIA
T2906
Synonym: Tanshinone B,Dan Shen ketone
Target: VEGFR
Xanthatin
T3S0153
Synonym:
Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial
L-Arginine
T3S0364
Synonym: L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
Adrenic Acid
T19180
Synonym: cis-7,10,13,16-Docosatetraenoic acid
Target: Endogenous Metabolite
Mollugin
T3673
Synonym: Rubimaillin
Target: HER, JAK
Oglufanide
T7203
Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
Orobol
TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon
Target: BCL, Caspase, PI3K
Albendazole
T1152
Synonym: SKF-62979
Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite
Pentoxifylline
T0070
Synonym: Oxpentifylline,PTX,BL-191
Target: HIV Protease, PDE, Adenosine Receptor, Autophagy
Chloramphenicol
T1205
Synonym: Chlornitromycin,Levomycetin,Chloromycetin
Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic
Pamufetinib
T13108
Synonym: H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115
Target: VEGFR, c-Met/HGFR
5Z-7-Oxozeaenol
T14055
Synonym: FR148083,L783279,LL-Z 1640-2
Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src
Sodium taurocholate
TWA2417
Synonym: Taurocholate Sodium
Target: Others
Casticin
T6S1373
Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin
Target: STAT
Diosmin
T0878
Synonym: Venosmine,Diosmil,Barosmin
Target: Aryl Hydrocarbon Receptor, Norepinephrine
Acetagastrodin
T8178
Synonym: Acegastrodine
Target: Others
Desmosterol
T19711
Synonym: Desmesterol,24-Dehydrocholesterol
Target: Endogenous Metabolite
Parishin B
T3S1816
Synonym:
Target: Others
Astragaloside III
T5S0833
Synonym:
Target: Antioxidant
Gentisin
TN1683
Synonym:
Target: DNA/RNA Synthesis
Orientin
T6S0721
Synonym: Lutexin,Luteolin-8-glucoside
Target: Others
Corynoxeine
T6S0655
Synonym:
Target: ERK
Procyanidin B2
T6S1367
Synonym: Proanthocyanidin B2
Target: Reactive Oxygen Species, NOD
(2S)-Isoxanthohumol
T4S0999
Synonym: Isoxanthohumol
Target: Virus Protease, HSV
Nothofagin
TN1996
Synonym:
Target: ERK, IL Receptor, TNF
Flavanone
T0530
Synonym: 2-Phenyl-4-chromanone,4-Flavanone,2,3-Dihydroflavone,2-Phenylchroman-4-one
Target: Others, Aromatase
Deoxypodophyllotoxin
TN1087
Synonym:
Target: Apoptosis, Microtubule Associated, Autophagy
Ethyl 3,4-dihydroxybenzoate
T5684
Synonym:
Target: Apoptosis, Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, NO Synthase, Autophagy
Norepinephrine
T7044
Synonym: Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol
Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy
Allicin
T3123
Synonym:
Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection
Polydatin
T3427
Synonym: Piceid,Polydotin Peceid
Target: Apoptosis, Mitophagy, NF-κB, Autophagy
Liensinine diperchlorate
T4S1102
Synonym: Liensinine-Perchlorate
Target: Mitophagy, Others, Autophagy
Chebulic acid
TN1042
Synonym:
Target: Others
Desloratadine
T2520
Synonym: Sch34117,NSC 675447
Target: Endogenous Metabolite, Histamine Receptor
Pentagalloylglucose
T3794
Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose
Target: Influenza Virus
Glabridin
T3403
Synonym: Q-100692,KB-289522,LS-176045
Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR
Yunaconitine
T5S1889
Synonym: Guayewuanine B
Target: Others
Caffeic Acid Phenethyl Ester
T6429
Synonym: Phenylethyl Caffeate,CAPE
Target: Apoptosis, NF-κB
Brazilin
T6S1784
Synonym: Natural Red 24,Braziletto,Brasilin,Superbresiline
Target: Apoptosis, Others, AMPK, Autophagy
N-(p-Coumaroyl) serotonin
TN1969
Synonym:
Target: PDGFR
Praeruptorin C
T6S1418
Synonym:
Target: Antioxidant, Calcium Channel
Sauchinone
T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03156 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) Mouse,Rat HEK293
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His) Human Human Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-02432 VEGF164 Protein, Rat, Recombinant Rat Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated Human,Cynomolgus HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01717 VEGF164 Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPJ-00864 VEGF165 Protein, Human, Recombinant Human Human Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-01830 VCAM-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-03698 VEGF121b Protein, Human, Recombinant Human HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-01007 VEGFC Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01008 VEGFD Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Human Human Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPJ-00603 TL1A Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-03155 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) Mouse,Rat HEK293
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-03305 VE-Cadherin Protein, Rat, Recombinant (His) Rat HEK293
Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPY-03705 VEGF164 Protein, Canine, Recombinant Canine HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPJ-00930 VCAM-1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1...
TMPY-03080 VEGF165 Protein, Danio rerio (zebrafish), Recombinant Danio rerio (zebrafish) Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01677 VE-Cadherin Protein, Human, Recombinant (His & hFc) Human HEK293
Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPY-04327 VEGFB Protein, Human, Recombinant (hFc) Human HEK293
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positive...
TMPY-01144 VCAM-1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPJ-00844 ANXA8 Protein, Human, Recombinant Human E. coli
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ...
TMPY-03200 VEGFD Protein, Rat, Recombinant (hFc) Rat HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-01656 VEGF183 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-05798 VEGF145 Protein, Human, Recombinant Human HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-05616 VCAM-1 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-00948 VCAM-1 Protein, Human, Recombinant (His) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-06916 VCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-01237 VE-Cadherin Protein, Mouse, Recombinant (His) Mouse HEK293
Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in ...
TMPJ-00377 VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Int...
TMPY-03150 VEGFD Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-02589 VEGFD Protein, Mouse, Recombinant (hFc) Mouse HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc) Human Human Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPJ-00380 AOC3 Protein, Human, Recombinant (His) Human Human Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i...
TMPJ-01030 JAM-B Protein, Human, Recombinant (hFc) Human Human Cells
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) wit...
TMPJ-01031 JAM-B Protein, Human, Recombinant (His) Human Human Cells
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) wit...
TMPJ-00414 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated Human Human Cells
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPJ-00593 VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His) Human Human Cells
Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi) Human HEK293
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His) Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPY-01168 ALK-1 Protein, Human, Recombinant (His) Human HEK293
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ...
TMPY-04168 ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02474 ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-01321 DLL4 Protein, Human, Recombinant (His) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02808 CD39 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-04644 PDGFB Protein, Human, Recombinant (His) Human Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00930 TIE2 Protein, Human, Recombinant (His & hFc) Human HEK293
TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play...
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VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)
TMPY-03156
Species: Mouse,Rat
Expression System: HEK293
VEGF121 Protein, Human, Recombinant (His)
TMPJ-00865
Species: Human
Expression System: Human Cells
VEGF164 Protein, Rat, Recombinant
TMPY-02432
Species: Rat
Expression System: Baculovirus-Insect Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293
VEGF164 Protein, Mouse, Recombinant
TMPY-01717
Species: Mouse
Expression System: Baculovirus-Insect Cells
VEGF165 Protein, Human, Recombinant
TMPJ-00864
Species: Human
Expression System: Human Cells
VCAM-1 Protein, Mouse, Recombinant (His)
TMPY-01830
Species: Mouse
Expression System: HEK293
VEGF121b Protein, Human, Recombinant
TMPY-03698
Species: Human
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc)
TMPY-00947
Species: Human
Expression System: HEK293
VEGFC Protein, Human, Recombinant (His)
TMPY-01007
Species: Human
Expression System: HEK293
VEGFD Protein, Human, Recombinant (His)
TMPY-01008
Species: Human
Expression System: HEK293
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
TMPJ-00412
Species: Human
Expression System: Human Cells
TL1A Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)
TMPY-03155
Species: Mouse,Rat
Expression System: HEK293
VE-Cadherin Protein, Rat, Recombinant (His)
TMPY-03305
Species: Rat
Expression System: HEK293
VEGF164 Protein, Canine, Recombinant
TMPY-03705
Species: Canine
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (hFc)
TMPJ-00930
Species: Mouse
Expression System: Human Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant
TMPY-03080
Species: Danio rerio (zebrafish)
Expression System: Baculovirus-Insect Cells
VE-Cadherin Protein, Human, Recombinant (His & hFc)
TMPY-01677
Species: Human
Expression System: HEK293
VEGFB Protein, Human, Recombinant (hFc)
TMPY-04327
Species: Human
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01144
Species: Mouse
Expression System: HEK293
ANXA8 Protein, Human, Recombinant
TMPJ-00844
Species: Human
Expression System: E. coli
VEGFD Protein, Rat, Recombinant (hFc)
TMPY-03200
Species: Rat
Expression System: HEK293
VEGF183 Protein, Human, Recombinant
TMPY-01656
Species: Human
Expression System: Baculovirus-Insect Cells
VEGF145 Protein, Human, Recombinant
TMPY-05798
Species: Human
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05616
Species: Human
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (His)
TMPY-00948
Species: Human
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06916
Species: Human
Expression System: HEK293
VE-Cadherin Protein, Mouse, Recombinant (His)
TMPY-01237
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00377
Species: Human
Expression System: Human Cells
VEGFD Protein, Mouse, Recombinant (His)
TMPY-03150
Species: Mouse
Expression System: HEK293
VEGFD Protein, Mouse, Recombinant (hFc)
TMPY-02589
Species: Mouse
Expression System: HEK293
AOC3 Protein, Human, Recombinant (hFc)
TMPJ-00379
Species: Human
Expression System: Human Cells
AOC3 Protein, Human, Recombinant (His)
TMPJ-00380
Species: Human
Expression System: Human Cells
JAM-B Protein, Human, Recombinant (hFc)
TMPJ-01030
Species: Human
Expression System: Human Cells
JAM-B Protein, Human, Recombinant (His)
TMPJ-01031
Species: Human
Expression System: Human Cells
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated
TMPJ-00414
Species: Human
Expression System: Human Cells
VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)
TMPJ-00593
Species: Human
Expression System: Human Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
TMPK-00823
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (aa 1-328, His)
TMPY-00637
Species: Human
Expression System: HEK293
ALK-1 Protein, Human, Recombinant (His)
TMPY-01168
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-04168
Species: Cynomolgus,Rhesus
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
TMPY-02474
Species: Mouse
Expression System: HEK293
DLL4 Protein, Human, Recombinant (His)
TMPY-01321
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
CD39 Protein, Mouse, Recombinant (His)
TMPY-02808
Species: Mouse
Expression System: Baculovirus-Insect Cells
PDGFB Protein, Human, Recombinant (His)
TMPY-04644
Species: Human
Expression System: Yeast
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
TIE2 Protein, Human, Recombinant (His & hFc)
TMPY-00930
Species: Human
Expression System: HEK293
Cat No. Product Name
L5400 Anti-Cardiovascular Disease Compound Library

1428 compounds
A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L2193 Anti-Liver Cancer Compound Library

1816 compounds
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L7110 Anti-Hypertension Compound Library

719 compounds
719 hypertension-related small molecules for high-throughput and high-content screening.
L1120 AMPK-Targeted Compound Library

80 compounds
80 well-chosen unique AMPK-targeted small molecules;
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
L7500 Coagulation and Anticoagulation Compound Library

154 compounds
A unique collection of 154 procoagulation and anticoagulation related compounds for high throughput screening (HTS) and high content screening (HCS);
TargetMol