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Alrestatin

🥰Excellent
Catalog No. T5195Cas No. 51411-04-2
Alias AY-22284

Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.

Alrestatin

Alrestatin

🥰Excellent
Purity: 99.23%
Catalog No. T5195Alias AY-22284Cas No. 51411-04-2
Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
Pack SizePriceAvailabilityQuantity
5 mg$38In Stock
10 mg$58In Stock
25 mg$92In Stock
50 mg$119In Stock
100 mg$197In Stock
200 mg$319In Stock
1 mL x 10 mM (in DMSO)$42In Stock
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Purity:99.23%
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Product Introduction

Bioactivity
Description
Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.
AliasAY-22284
Chemical Properties
Molecular Weight255.2256
FormulaC14H9NO4
Cas No.51411-04-2
SmilesOC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23
Relative Density.1.511g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (97.95 mM)
H2O: Insoluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9181 mL19.5905 mL39.1810 mL195.9051 mL
5 mM0.7836 mL3.9181 mL7.8362 mL39.1810 mL
10 mM0.3918 mL1.9591 mL3.9181 mL19.5905 mL
20 mM0.1959 mL0.9795 mL1.9591 mL9.7953 mL
50 mM0.0784 mL0.3918 mL0.7836 mL3.9181 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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