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SAR131675

🥰Excellent
Catalog No. T6012Cas No. 1433953-83-3
Alias SAR 131675

SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.

SAR131675

SAR131675

🥰Excellent
Purity: 99.68%
Catalog No. T6012Alias SAR 131675Cas No. 1433953-83-3
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$67In Stock
10 mg$115In Stock
25 mg$238In Stock
50 mg$362In Stock
100 mg$543In Stock
200 mg$653In Stock
1 mL x 10 mM (in DMSO)$78In Stock
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Purity:99.68%
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Product Introduction

Bioactivity
Description
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
Targets&IC50
VEGFR3:23 nM
AliasSAR 131675
Chemical Properties
Molecular Weight358.39
FormulaC18H22N4O4
Cas No.1433953-83-3
SmilesC(C)N1C=2C(C(=O)C(C(NC)=O)=C1N)=CC=C(C#C[C@@](COC)(C)O)N2
Relative Density.1.33 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 70 mg/mL (195.32 mM), when pH is adjusted to 2 with HCl. Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7903 mL13.9513 mL27.9026 mL139.5128 mL
5 mM0.5581 mL2.7903 mL5.5805 mL27.9026 mL
10 mM0.2790 mL1.3951 mL2.7903 mL13.9513 mL
20 mM0.1395 mL0.6976 mL1.3951 mL6.9756 mL
50 mM0.0558 mL0.2790 mL0.5581 mL2.7903 mL
100 mM0.0279 mL0.1395 mL0.2790 mL1.3951 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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