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Ritodrine hydrochloride

Catalog No. T1433Cas No. 23239-51-2
Alias Ritodrine HCl, NSC 291565, DU21220

Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.

Ritodrine hydrochloride

Ritodrine hydrochloride

Purity: 99.89%
Catalog No. T1433Alias Ritodrine HCl, NSC 291565, DU21220Cas No. 23239-51-2
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.
Pack SizePriceAvailabilityQuantity
200 mg$30In Stock
500 mg$35In Stock
1 g$48In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.89%
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Product Introduction

Bioactivity
Description
Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.
AliasRitodrine HCl, NSC 291565, DU21220
Chemical Properties
Molecular Weight323.82
FormulaC17H21NO3·HCl
Cas No.23239-51-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 200.7 mM
DMSO: 50 mg/mL (154.41 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.0881 mL15.4407 mL30.8814 mL154.4068 mL
5 mM0.6176 mL3.0881 mL6.1763 mL30.8814 mL
10 mM0.3088 mL1.5441 mL3.0881 mL15.4407 mL
20 mM0.1544 mL0.7720 mL1.5441 mL7.7203 mL
50 mM0.0618 mL0.3088 mL0.6176 mL3.0881 mL
100 mM0.0309 mL0.1544 mL0.3088 mL1.5441 mL

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