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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $59 | In Stock | |
2 mg | $86 | In Stock | |
5 mg | $143 | In Stock | |
10 mg | $226 | In Stock | |
25 mg | $458 | In Stock | |
50 mg | $656 | In Stock | |
100 mg | $919 | In Stock |
Description | BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM). |
Targets&IC50 | PTEN:14 nM(Cell-free assay) |
In vitro | 1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1] |
Alias | bpV (HOpic) |
Molecular Weight | 347.24 |
Formula | C6H4K2NO8V |
Cas No. | 722494-26-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | H2O: 10 mM DMSO: Insoluble | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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