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CAY10678

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Purity:99.66%

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COA HNMR HPLC

CAY10678

Catalog No. T38369Cas No. 1268709-57-4

CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$48	In Stock
5 mg	$123	In Stock
10 mg	$189	In Stock
25 mg	$372	In Stock
50 mg	$562	In Stock
100 mg	$793	In Stock
500 mg	$1,630	In Stock
1 mL x 10 mM (in DMSO)	$225	In Stock

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Product Introduction

Bioactivity

Description

CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS

Chemical Properties

Molecular Weight	382.54
Formula	C23H34N4O
Cas No.	1268709-57-4

Storage & Solubility Information

Storage

store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 1 mg/mL (2.61 mM)

Ethanol:PBS (pH 7.2) (1:8): 0.1 mg/mL

Ethanol: 10 mg/mL (26.14 mM)

DMF: 8 mg/mL (20.91 mM)

H2O: < 0.1 mg/mL (insoluble.)

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6141 mL	13.0705 mL	26.1411 mL	130.7053 mL

Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.5228 mL	2.6141 mL	5.2282 mL	26.1411 mL
10 mM	0.2614 mL	1.3071 mL	2.6141 mL	13.0705 mL
20 mM	0.1307 mL	0.6535 mL	1.3071 mL	6.5353 mL
50 mM	0.0523 mL	0.2614 mL	0.5228 mL	2.6141 mL
100 mM	0.0261 mL	0.1307 mL	0.2614 mL	1.3071 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc