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Ceftazidime Pentahydrate

Catalog No. T8261Cas No. 78439-06-2

Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.

Ceftazidime Pentahydrate

Ceftazidime Pentahydrate

Purity: 99.39%
Catalog No. T8261Cas No. 78439-06-2
Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.
Pack SizePriceAvailabilityQuantity
500 mg$60In Stock
1 g$88In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.39%
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Product Introduction

Bioactivity
Description
Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli, including Pseudomonas aeruginosa, and is used in the study of infectious diseases.
In vitro
In Pseudomonas aeruginosa strains (PAO1, PA1, PA2), Ceftazidime pentahydrate (approximately 0-8 µg/mL; 24 h) demonstrated antibacterial and anti-biofilm activities, with minimum inhibitory concentration (MIC) values of 2-4 µg/mL[2].
In vivo
In the murine thigh infection model, Ceftazidime Pentahydrate (2000 mg; administered via a 2-hour intravenous infusion every 8 hours for a total of 24 hours) was able to reduce the bacterial density against the isogenic NDM (New Delhi metallo-β-lactamase) strain[4].
Chemical Properties
Molecular Weight636.65
FormulaC22H32N6O12S2
Cas No.78439-06-2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (125.66 mM), Sonication is recommended.
H2O: 20 mg/mL (31.41 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.5707 mL7.8536 mL15.7072 mL78.5361 mL
5 mM0.3141 mL1.5707 mL3.1414 mL15.7072 mL
10 mM0.1571 mL0.7854 mL1.5707 mL7.8536 mL
20 mM0.0785 mL0.3927 mL0.7854 mL3.9268 mL
DMSO
1mg5mg10mg50mg
50 mM0.0314 mL0.1571 mL0.3141 mL1.5707 mL
100 mM0.0157 mL0.0785 mL0.1571 mL0.7854 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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