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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $38 | In Stock | |
5 mg | $82 | In Stock | |
10 mg | $118 | In Stock | |
25 mg | $193 | In Stock | |
50 mg | $286 | In Stock |
Description | Demeclocycline (Declostatin) is a tetracycline antibiotic produced by a strain of Streptomyces aureofaciens.Demeclocycline has antimicrobial activity and inhibits the action of vasopressin on the renal tubules, leading to diuresis. Demeclocycline can be used to induce diuresis and acute renal failure. |
In vitro | Demeclocycline (10 μM; 24 h) is a novel BTICs growth inhibitor, which can directly stimulate the activity of monocytes and macrophages[4]. |
In vivo | Demeclocycline (40 mg/kg; intraperitoneal injection; once daily; for 48 hours) resulted in increased urine volume, decreased urine osmolality, and significantly increased fractional excretion of water[3]. |
Alias | Ledermycin, Bioterciclin, Deteclo, Declostatin, Deganol |
Molecular Weight | 464.85 |
Formula | C21H21ClN2O8 |
Cas No. | 127-33-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | H2O: 20 mg/mL (43.02 mM), Sonication is recommended. DMSO: 10 mg/mL (21.51 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO/H2O
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