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DS20362725
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Catalog No. T60759Cas No. 2735803-20-8
Alias DS 20362725
DS20362725 is a selective estrogen-related receptor alpha (ERRα) agonist that binds to ERRα and enhances its transcriptional activity while preventing ERRα from binding to its repressor, receptor-interacting protein 140 (RIP140), commonly used in the study of metabolic disorders.
DS20362725
😃Good
Purity: 99.34%
Catalog No. T60759Alias DS 20362725Cas No. 2735803-20-8
DS20362725 is a selective estrogen-related receptor alpha (ERRα) agonist that binds to ERRα and enhances its transcriptional activity while preventing ERRα from binding to its repressor, receptor-interacting protein 140 (RIP140), commonly used in the study of metabolic disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,200 | 6-8 weeks | |
| 50 mg | $1,570 | 6-8 weeks | |
| 100 mg | $2,570 | 6-8 weeks |
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Purity:99.34%
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Product Introduction
Bioactivity
Chemical Properties
| Description | DS20362725 is a selective estrogen-related receptor alpha (ERRα) agonist that binds to ERRα and enhances its transcriptional activity while preventing ERRα from binding to its repressor, receptor-interacting protein 140 (RIP140), commonly used in the study of metabolic disorders. |
| In vitro | Treatment of MG63 cells with DS20362725 (0.002, 0.006, 0.017, 0.051, 0.015, 0.046, 1.4, 4.2, 12.5 μg/mL, 18 hours) activated the transcriptional activity of full-length ERRα with an EC50 value of 1.1 μM. [1] |
| Alias | DS 20362725 |
| Molecular Weight | 310.39 |
| Formula | C19H22N2O2 |
| Cas No. | 2735803-20-8 |
| Smiles | OC1=CC=C(OC=2C=CC=3N=C(N(C3C2)C)C)C=C1C(C)(C)C |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (16.11 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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