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DS20362725
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DS20362725
Catalog No. T60759Cas No. 2735803-20-8
DS20362725 is an agonist of estrogen-related receptor α (ERRα) that is able to be used for the metabolic disorders research, for example, type 2 diabetes mellitus (T2DM). The IC 50 value of DS20362725 inhibiting the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) is 0.6 μM [1].
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,200 | 6-8 weeks | |
| 50 mg | $1,570 | 6-8 weeks | |
| 100 mg | $2,570 | 6-8 weeks |
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Chemical Properties
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| Description | DS20362725 is an agonist of estrogen-related receptor α (ERRα) that is able to be used for the metabolic disorders research, for example, type 2 diabetes mellitus (T2DM). The IC 50 value of DS20362725 inhibiting the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) is 0.6 μM [1]. |
| In vitro | DS20362725 (compound 3d; concentrations: 0.002, 0.006, 0.017, 0.051, 0.015, 0.046, 1.4, 4.2, 12.5 μg/mL; duration: 18 h) effectively suppresses the transcriptional activity of the full-length ERRα in MG63 cells, achieving an EC50 of 1.1 μM [1]. |
| Molecular Weight | 310.39 |
| Formula | C19H22N2O2 |
| Cas No. | 2735803-20-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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