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Eicosapentaenoic acid ethyl ester

🥰Excellent
Catalog No. T7068Cas No. 86227-47-6
Alias Icosapent ethyl, Ethyl eicosapentaenoate, EPA ethyl ester

Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) is an omega-3 fatty acid.

Eicosapentaenoic acid ethyl ester

Eicosapentaenoic acid ethyl ester

🥰Excellent
Purity: 98.13%
Catalog No. T7068Alias Icosapent ethyl, Ethyl eicosapentaenoate, EPA ethyl esterCas No. 86227-47-6
Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) is an omega-3 fatty acid.
Pack SizePriceAvailabilityQuantity
50 mg$50In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:98.13%
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Product Introduction

Bioactivity
Description
Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) is an omega-3 fatty acid.
In vivo
Icosapent ethyl (IPE) 4 g/day significantly reduced large VLDL, total LDL, small LDL, and total HDL particle concentrations and VLDL particle size in patients with TG 500 mg/dL.Changes in VLDL particle concentration and size reflect the TG-lowering effects of eicosapentaenoic acid.?The reduction in LDL particle concentration with IPE is novel among ω-3 therapies and is consistent with the previously reported reduction in apolipoprotein B and lack of LDL-C increase with IPE in patients with very high TG levels.
AliasIcosapent ethyl, Ethyl eicosapentaenoate, EPA ethyl ester
Chemical Properties
Molecular Weight330.5
FormulaC22H34O2
Cas No.86227-47-6
SmilesCCOC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CC
Relative Density.0.91 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 33.33 mg/mL (100.85 mM), Sonication is recommended.
Ethanol: 50 mg/mL (151.29 mM), Sonication is recommended.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM3.0257 mL15.1286 mL30.2572 mL151.2859 mL
5 mM0.6051 mL3.0257 mL6.0514 mL30.2572 mL
10 mM0.3026 mL1.5129 mL3.0257 mL15.1286 mL
20 mM0.1513 mL0.7564 mL1.5129 mL7.5643 mL
50 mM0.0605 mL0.3026 mL0.6051 mL3.0257 mL
100 mM0.0303 mL0.1513 mL0.3026 mL1.5129 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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