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Ergosta-7,22-dien-3-one
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Catalog No. TN3983Cas No. 32507-77-0
Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis. It exhibits pro-inflammatory properties, stimulating nitric oxide production, inducing gene expression, and promoting the production of TLRs, cytokines, chemokines, and cellular adhesion molecules.
Ergosta-7,22-dien-3-one
😃Good
Catalog No. TN3983Cas No. 32507-77-0
Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis. It exhibits pro-inflammatory properties, stimulating nitric oxide production, inducing gene expression, and promoting the production of TLRs, cytokines, chemokines, and cellular adhesion molecules.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $1,168 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,408 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis. It exhibits pro-inflammatory properties, stimulating nitric oxide production, inducing gene expression, and promoting the production of TLRs, cytokines, chemokines, and cellular adhesion molecules. |
| In vitro | Ergosta-7,22-dien-3-one, isolated from a wild Mexican strain of Ganoderma oerstedii. According study, Ergosta-7,22-dien-3-one did not present any cytotoxic effect on HeLa or J774A.1 cells, and it was able to stimulate nitric oxide production, induce the expression of genes, and induce the production of TLRs, cytokines, chemokines, and cellular adhesion molecules in J774A.1 cells, based on reverse-transcriptase polymerase chain reaction and enzyme-linked immunosorbent assay. Here we report a new pro-inflammatory property of Ergosta-7,22-dien-3-one, which should be considered as a possible adjuvant property in view of its biological activity.[1] |
| Molecular Weight | 396.65 |
| Formula | C28H44O |
| Cas No. | 32507-77-0 |
| Smiles | C[C@@]12[C@](C=3[C@@]([C@]4(C)C(CC3)(CC(=O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](C=C[C@@H](C(C)C)C)C)[H])[H] |
| Relative Density. | 0.99 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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