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FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 29 € | In Stock | |
5 mg | 99 € | In Stock | |
10 mg | 167 € | In Stock | |
25 mg | 341 € | In Stock | |
50 mg | 549 € | In Stock | |
100 mg | 784 € | In Stock | |
200 mg | 1.035 € | In Stock |
Description | FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively. |
Targets&IC50 | COX-2:65 µM, COX-1:28 nM |
Alias | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride, 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride |
Molecular Weight | 459.99 |
Formula | C23H26ClN3O3S |
Cas No. | 130717-51-0 |
Smiles | CN1CCN(CC1)C(=O)C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC.Cl |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 4 mg/mL (8.70 mM) H2O: 2 mg/mL (4.35 mM) | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O/DMSO
DMSO
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