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Golgicide A
🥰Excellent
Catalog No. T6516Cas No. 1139889-93-2
Golgicide A is a potent and rapidly reversible GBF1 inhibitor.
Golgicide A
🥰Excellent
Purity: 99.75%
Catalog No. T6516Cas No. 1139889-93-2
Golgicide A is a potent and rapidly reversible GBF1 inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $36 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $198 | In Stock | |
| 50 mg | $328 | In Stock | |
| 100 mg | $529 | In Stock | |
| 500 mg | $1,130 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $63 | In Stock |
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Purity:99.75%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Golgicide A is a potent and rapidly reversible GBF1 inhibitor. |
| In vitro | Golgicide A inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM. Golgicide A causes a decrease in GBF1-mediated Arf1 activation, arrests secretion of soluble and membrane-anchored proteins and then impairs retrograde toxin transport. [1] Golgicide A decreases HCV RNA levels in FLRP1 cells and J6/JFH1 cells. In addition, Golgicide A causes redistribution of NS5A and accumulation of infectious viral particles in J6/JFH1 cells. [2] |
| Molecular Weight | 284.3 |
| Formula | C17H14F2N2 |
| Cas No. | 1139889-93-2 |
| Smiles | Fc1cc(F)c2NC([C@@H]3CC=C[C@@H]3c2c1)c1cccnc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 14.2 mg/mL (50 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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