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hDHODH-IN-7

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Catalog No. T11031Cas No. 1644156-41-1
Alias DHODH-IN-9

hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.

hDHODH-IN-7

hDHODH-IN-7

🥰Excellent
Purity: 99.82%
Catalog No. T11031Alias DHODH-IN-9Cas No. 1644156-41-1
hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
2 mg$175In Stock
5 mg$269In Stock
10 mg$395In Stock
25 mg$592In Stock
50 mg$834In Stock
100 mg$1,120In Stock
500 mg$2,260In Stock
1 mL x 10 mM (in DMSO)$280In Stock
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Purity:99.82%
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Product Introduction

Bioactivity
Description
hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor. hDHODH-IN-7 and pMIC50 of 7.4 have antiviral effects.
Targets&IC50
DHODH:pMIC50:7.4
In vitro
hDHODH-IN-7 is the corresponding pyridazine homologue from 3-chloro-6-cyclopropylpyridazine. There is almost no change, and the antiviral mode of action of the analogs with 5-cyclopyridine reflects the antiviral effect of homologues with 5-ethylpyrimidinyl groups to some extent. hDHODH-IN-7 is a good antiviral agent for such analogs[1].
AliasDHODH-IN-9
Chemical Properties
Molecular Weight366.43
FormulaC21H23FN4O
Cas No.1644156-41-1
SmilesC(C=1C(OC(C)C)=NN(C1C)C=2N=CC(=CN2)C3CC3)C4=C(F)C=CC=C4
Relative Density.1.27 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (136.45 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7290 mL13.6452 mL27.2903 mL136.4517 mL
5 mM0.5458 mL2.7290 mL5.4581 mL27.2903 mL
10 mM0.2729 mL1.3645 mL2.7290 mL13.6452 mL
20 mM0.1365 mL0.6823 mL1.3645 mL6.8226 mL
50 mM0.0546 mL0.2729 mL0.5458 mL2.7290 mL
100 mM0.0273 mL0.1365 mL0.2729 mL1.3645 mL

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